Biological Activity
Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.59 mL | 57.94 mL | 115.89 mL |
0.5 mM | 2.32 mL | 11.59 mL | 23.18 mL |
1 mM | 1.16 mL | 5.79 mL | 11.59 mL |
5 mM | 0.23 mL | 1.16 mL | 2.32 mL |
*The above data is based on the productmolecular weight 862.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13178 |
---|---|
Actions | Antagonist |
M. Wt | 862.91 |
Formula | C46H54O16 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 187269-40-5 |
Synonyms | TBC 1269, TBC1269, TBC-1269 |
SMILES | OC[[email protected]]([[email protected]@H](O)[[email protected]](O)[[email protected]@H]1O)O[[email protected]@H]1OC(C=C2)=C(C3=CC(CC(O)=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O)=O)=CC=C5)=C4O[[email protected]]6O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]@H]6O)CO |
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