BIMU 8 is a highly selective agonist of the 5-HT4 receptor, demonstrating EC50 values of 18 nM for the wild type receptor, 77 nM for the T3.36A mutant, and 540 nM for the W6.48A mutant. This compound facilitates research into serotonin signaling pathways and may have applications in studying gastrointestinal motility and cognitive disorders related to the 5-HT4 receptor. Scientists can leverage BIMU 8's potency and selectivity for detailed pharmacological investigations.
BIMU 8 is a highly selective agonist of the 5-HT4 receptor, demonstrating EC50 values of 18 nM for the wild type receptor, 77 nM for the T3.36A mutant, and 540 nM for the W6.48A mutant. This compound facilitates research into serotonin signaling pathways and may have applications in studying gastrointestinal motility and cognitive disorders related to the 5-HT4 receptor. Scientists can leverage BIMU 8's potency and selectivity for detailed pharmacological investigations.
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