Fig. 1 · Structure
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Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide
Protein Labeling
Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide functions as a versatile protein labeling reagent through its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, this compound facilitates ring strain-promoted alkyne-azide cycloaddition (SPAAC) in the presence of dibenzocyclooctyne (DBCO) or bicyclononyne (BCN). Its acid-cleavable properties enhance enrichment of cell surface glycoproteins, making it a valuable tool for studying protein interactions and cell surface markers in various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2599839-59-3 |
| Applications | Protein Labeling |
| Formula | C47H67N9O10SSi |
| Molecular Weight | 978.24 |
| SMILES | O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(NCCOCCOCCOCCOCCC(NCC(C)(C)O[Si](C3=CC=CC=C3)(C4=CC=CC=C4)OCCCNC(C5=CN=C(CN=[N+]=[N-])C=C5)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.