Biotin-PEGn-NHS ester is a biotinylated linker that facilitates the synthesis of PROTAC molecules by targeting liposomal delivery systems. This compound demonstrates the ability to bind with free neutral avidin, enhancing the specificity for malignant glioma cells. Additionally, Biotin-PEGn-NHS ester can be conjugated to amino groups in GelMA to create biotin-modified functionalized hydrogels, such as gelatin methacryloyl (Bio-GelMA), enabling advanced applications in tissue engineering and drug delivery.
Biotin-PEGn-NHS ester is a biotinylated linker that facilitates the synthesis of PROTAC molecules by targeting liposomal delivery systems. This compound demonstrates the ability to bind with free neutral avidin, enhancing the specificity for malignant glioma cells. Additionally, Biotin-PEGn-NHS ester can be conjugated to amino groups in GelMA to create biotin-modified functionalized hydrogels, such as gelatin methacryloyl (Bio-GelMA), enabling advanced applications in tissue engineering and drug delivery.
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