Fig. 1 · Structure
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Biotin-TAT (47-57)
Biotin Tagged TAT
Biotin-TAT (47-57) is a biotin-tagged transactivator of transcription, functioning primarily as a protein transduction domain (PTD). This reagent promotes the efficient delivery of biomolecules into various primary cells via an ATP- and temperature-dependent mechanism, suggesting a reliance on endocytic pathways for cellular uptake. Biotin-TAT (47-57) is extensively utilized in research applications that require the introduction of peptides, proteins, or nucleic acids into living cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1231898-25-1 |
| Applications | Biotin Tagged TAT |
| Formula | C74H132N34O16S |
| Molecular Weight | 1786.12 |
| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)[C@@]1([H])NC(=O)N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.