Fig. 1 · Structure
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Bisnoralcohol
RANKL Inhibitor
Bisnoralcohol is a potent RANKL inhibitor with an IC50 of 2.325 μM, effectively blocking RANKL-induced osteoclastogenesis. This compound demonstrates significant antiosteoporosis activity, making it valuable for research in bone metabolism and related disorders. It serves as a useful tool for studies aimed at elucidating the mechanisms of osteoclast regulation and developing therapeutic strategies against osteoporosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 40736-33-2 |
| Applications | RANKL Inhibitor |
| Formula | C22H34O2 |
| Molecular Weight | 330.50 |
| SMILES | C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]3[C@H]2CCC4=CC(CC[C@]34C)=O)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.