Fig. 1 · Structure
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Bisoxatin
S-protein-ACE2 Inhibitor
Bisoxatin is a potent inhibitor of the S-protein-ACE2 interface, which is crucial for SARS-CoV-2 entry into host cells. Originally developed as a laxative for the treatment of constipation, Bisoxatin's ability to effectively block this interaction positions it as a candidate for research into therapeutic strategies against COVID-19. Its inhibitory action provides valuable insights for studies aimed at understanding viral entry mechanisms and developing antiviral agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 17692-24-9 |
| Applications | S-protein-ACE2 Inhibitor |
| Formula | C20H15NO4 |
| Molecular Weight | 333.34 |
| SMILES | O=C1C(C2=CC=C(C=C2)O)(OC3=CC=CC=C3N1)C4=CC=C(C=C4)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.