Fig. 1 · Structure
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BITC-SG
GST P1-1 Inhibitor
BITC-SG is a conjugate of phenylisothiocyanate (BITC) and glutathione (GSH), primarily acting as an inhibitor of glutathione S-transferase P1-1 (GST P1-1). This compound exhibits irreversible inhibition of GST P1-1, which is implicated in various biological processes and diseases. BITC-SG is useful for research applications aimed at understanding the role of GST P1-1 in cellular detoxification and its potential as a therapeutic target in cancer and other pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 62959-30-2 |
| Applications | GST P1-1 Inhibitor |
| Formula | C18H24N4O6S2 |
| Molecular Weight | 456.54 |
| SMILES | S=C(NCC1=CC=CC=C1)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.