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Bizaxofusp

Fusion Protein

Bizaxofusp is a fusion protein that combines interleukin-4 (IL-4) with a truncated form of Pseudomonas exotoxin. This compound selectively binds to IL-4 receptors on tumor cells, facilitating internalization, and delivering its toxic moiety to inhibit protein synthesis, leading to apoptosis in these cancerous cells. Bizaxofusp is primarily utilized in cancer research, providing insights into targeted therapies and apoptotic mechanisms in tumor biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1236019-35-4
Applications	Fusion Protein
Synonyms	MDNA55; NBI-3001; PRX-321

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.