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Bleomycin A2

AspH inhibitor

Bleomycin A2 is an antitumor antibiotic that serves as an inhibitor of aspartate/asparagine-β-hydroxylase (AspH), demonstrating an IC50 of 1.47 μM. This compound induces DNA degradation, making it a valuable tool in cancer research. Its activity provides insights into the mechanisms of tumor cell proliferation and offers potential therapeutic routes for oncological studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	41432-97-7
Applications	AspH inhibitor
Formula	C₅₅H₈₅N₁₇O₂₅S₄
Molecular Weight	1512.62
SMILES	O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCC[S+](C)C)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@]6([H])[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O.O=S([O-])(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.