Fig. 1 · Structure
Documents & Downloads
BMH-9
NR2F6 Modulator
BMH-9 is a modulator targeting the nuclear receptor subfamily 2, group F, member 6 (NR2F6), also known as the nuclear orphan receptor Ear2. This compound acts as an activator of the p53 signaling pathway through its interaction with DNA, leading to the inhibition of proliferation in human cancer cells. BMH-9 has demonstrated notable antitumor efficacy in NOD-SCID mouse models, making it a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 457937-39-2 |
| Applications | NR2F6 Modulator |
| Formula | C19H27N3O2 |
| Molecular Weight | 329.44 |
| SMILES | O=C(OCC)C1=C(C2=CC(C)=CC(C)=C2N=C1)NCCCN(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.