Fig. 1 · Structure

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BMS-103

PDL1 Inhibitor

BMS-103 is a potent inhibitor of programmed death-ligand 1 (PDL1) with an IC50 of 79.1 nM and a binding affinity (kd) of 44 nM. This compound has been shown to decrease the survival rate of acute T-lymphoblastic leukemia and ovarian cancer cells. BMS-103 is suitable for research applications focused on targeting PDL1 in acute T-lymphoblastic leukemia and various malignancies, including ovarian cancer.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1675202-86-4
Applications PDL1 Inhibitor
Formula C25H29NO4
Molecular Weight 407.50
SMILES
CC1=C(COC2=CC(OC)=C(CNCCO)C(OC)=C2)C=CC=C1C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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