BMS-1233 is a potent inhibitor of programmed cell death-ligand 1 (PD-L1) with an IC50 of 14.5 nM. This compound promotes cytotoxicity in HepG2 cells within a Jurkat T cell and HepG2 co-culture model, demonstrating significant antitumor activity against melanoma in in vivo mouse models. BMS-1233 is suitable for research applications focused on cancer immunotherapy and the modulation of immune checkpoint pathways.
BMS-1233 is a potent inhibitor of programmed cell death-ligand 1 (PD-L1) with an IC50 of 14.5 nM. This compound promotes cytotoxicity in HepG2 cells within a Jurkat T cell and HepG2 co-culture model, demonstrating significant antitumor activity against melanoma in in vivo mouse models. BMS-1233 is suitable for research applications focused on cancer immunotherapy and the modulation of immune checkpoint pathways.
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