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BMS-188797

Taxane Analog

BMS-188797 is a novel Taxane analog that acts primarily by stabilizing microtubules, thereby disrupting mitotic spindle formation. This compound exhibits potent antitumor activity and has been shown to enhance the efficacy of radiotherapy in lung cancer models. Its mechanism makes it a valuable tool for investigating combination therapies and improving clinical outcomes in oncological research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	172481-83-3
Applications	Taxane Analog
Formula	C₄₇H₅₁NO₁₅
Molecular Weight	869.91
SMILES	COC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.