Fig. 1 · Structure

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BMS-191095 hydrochloride

Mitochondrial KATP Channel Opener

BMS-191095 hydrochloride is a mitochondrial KATP channel opener. It provides cardioprotective effects by prolonging contraction time during ischemia, enhancing contractile function post-reperfusion, and decreasing lactate dehydrogenase (LDHM) release. Research applications include studies on myocardial protection without vasodilation or alterations in electrophysiological parameters, contributing to a deeper understanding of cardiac metabolism and injury responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Opener
CAS Number 166095-95-0
Applications Mitochondrial KATP Channel Opener
Formula C22H22Cl2N4O2
Molecular Weight 445.34
SMILES
CC(O1)(C)[C@H](O)[C@@H](N(CC2=NC=CN2)C3=CC=C(Cl)C=C3)C4=C1C=CC(C#N)=C4.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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