BMS-192364 is a selective RGS (Regulator of G Protein Signaling) agonist that targets the Gα-RGS interaction, promoting the formation of an inactive Gα-RGS complex. This compound has been shown to reduce urinary bladder contraction and enhance the activity of GTPase-activating proteins (GAPs) on Gq proteins. Additionally, BMS-192364 inhibits calcium flux, making it a valuable tool for studying signaling pathways involved in bladder function and related physiological processes.
BMS-192364 is a selective RGS (Regulator of G Protein Signaling) agonist that targets the Gα-RGS interaction, promoting the formation of an inactive Gα-RGS complex. This compound has been shown to reduce urinary bladder contraction and enhance the activity of GTPase-activating proteins (GAPs) on Gq proteins. Additionally, BMS-192364 inhibits calcium flux, making it a valuable tool for studying signaling pathways involved in bladder function and related physiological processes.
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