Fig. 1 · Structure
Documents & Downloads
BMS-199264 hydrochloride
ATP Hydrolase Inhibitor
BMS-199264 hydrochloride is a selective inhibitor of F1F0 ATP hydrolase, demonstrating an IC50 of 0.5 μM, while not affecting F1F0 ATP synthase activity. This compound primarily targets ATP hydrolysis, effectively mitigating ATP depletion during ischemic conditions, which subsequently reduces cardiac necrosis. Additionally, BMS-199264 hydrochloride supports the restoration of contractile function following reperfusion, making it valuable for research related to cardiac ischemia and recovery.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 186180-83-6 |
| Applications | ATP Hydrolase Inhibitor |
| Formula | C26H32Cl2N4O4S |
| Molecular Weight | 567.53 |
| SMILES | O[C@@H]1C(C)(OC2=CC=C(C=C2[C@H]1N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)S(=O)(N5CCCCC5)=O)C.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.