BMS-210285

Catalog No.: A58658
β3 Receptor Agonist
BMS-210285 is a selective β3 adrenergic receptor agonist, demonstrating a Ki of 9 nM at the human β3-adrenoceptor. With an intrinsic activity of 83% relative to isoproterenol, it modulates metabolic pathways associated with energy expenditure and lipolysis. This compound is significant for research applications focusing on obesity and type 2 diabetes, aiding in the exploration of therapeutic strategies targeting metabolic disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionBMS-210285 is a selective β3 adrenergic receptor agonist, demonstrating a Ki of 9 nM at the human β3-adrenoceptor. With an intrinsic activity of 83% relative to isoproterenol, it modulates metabolic pathways associated with energy expenditure and lipolysis. This compound is significant for research applications focusing on obesity and type 2 diabetes, aiding in the exploration of therapeutic strategies targeting metabolic disorders.
Product Information
Catalog NumA58658
FormulaC24H25ClF2N2O5S
Molecular Weight526.98
CAS Number344607-69-8
SMILESCS(=O)(NC1=CC([C@@H](O)CN[C@@H](C2=CC=C(OC(F)F)C=C2)CC3=CC=CC(Cl)=C3)=CC=C1O)=O
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