Fig. 1 · Structure
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BMS-262084
factor XIa Inhibitor
BMS-262084 is a potent and selective irreversible inhibitor of factor XIa, exhibiting an IC50 of 2.8 nM against human factor XIa. Additionally, it inhibits human tryptase with an IC50 of 5 nM. BMS-262084 demonstrates significant antithrombotic effects, making it a valuable tool for research applications related to thrombus formation and anticoagulation therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 253174-92-4 |
| Applications | factor XIa Inhibitor |
| Formula | C18H31N7O5 |
| Molecular Weight | 425.48 |
| SMILES | CC(C)(NC(N1CCN(C(N2[C@H](C(O)=O)[C@@H](CCCNC(N)=N)C2=O)=O)CC1)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.