Fig. 1 · Structure

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BMS-269223

FXa Inhibitor

BMS-269223 is a potent and selective orally active inhibitor of factor Xa, demonstrating a Ki value of 6.5 nM and an effective concentration for 2x prothrombin time prolongation of 32 μM. This compound plays a crucial role in inhibiting thrombosis formation, making it an important tool for cardiovascular disease research. BMS-269223 facilitates the study of anticoagulant therapies and the underlying mechanisms of thrombotic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 288077-60-1
Applications FXa Inhibitor
Formula C23H28N6O3
Molecular Weight 436.51
SMILES
CC(O1)=CC2=C1C=CC(N/C(N[C@H]3CCCCN(CC(N4CCCC4)=O)C3=O)=N/C#N)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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