Fig. 1 · Structure
Documents & Downloads
BMS-279700
p56Lck Inhibitor
BMS-279700 is an orally active inhibitor of the Src-family kinase p56Lck. This compound demonstrates the capability to inhibit T cell proliferation and block the production of proinflammatory cytokines, including IL-2 and TNFα. BMS-279700 serves as a valuable tool for research in inflammation and immunology, facilitating studies on immune response modulation and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 240814-54-4 |
| Applications | p56Lck Inhibitor |
| Formula | C21H22ClN7 |
| Molecular Weight | 407.90 |
| SMILES | C[C@H](NCC1)CN1C2=CC=C3C(N4C(C(NC5=C(C=CC=C5Cl)C)=N3)=CN=C4)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.