Fig. 1 · Structure

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BMS-480404

kFABP/aP2 Inhibitor

BMS-480404 is a potent inhibitor of keratinocyte fatty acid-binding protein (kFABP) and adipocyte lipid-binding protein (aP2), exhibiting a Ki value of 33 nM for kFABP. This compound is primarily utilized in research related to metabolic disorders, providing insights into the regulation of lipid metabolism and adipocyte function. Its selective inhibition of kFABP and aP2 makes BMS-480404 a valuable tool for studying the underlying mechanisms of metabolic diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 533889-36-0
Applications kFABP/aP2 Inhibitor
Formula C22H18Cl2O5
Molecular Weight 433.28
SMILES
ClC(C=CC=C1)=C1COC2=C(C=CC=C2[C@H](O)C(O)=O)OCC3=C(C=CC=C3)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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