Fig. 1 · Structure
Documents & Downloads
BMS-496
DGKα/ζ Inhibitor
BMS-496 is a selective inhibitor of diacylglycerol kinase alpha (DGKα) and zeta (DGKζ), exhibiting IC50 values of 0.09 μM and 0.006 μM, respectively. This compound is crucial for studying the role of DGK isoforms in various cellular processes, including receptor signaling and lipid metabolism. BMS-496 is valuable for researching therapeutic strategies targeting DGK-related pathways in cancer, inflammation, and other diseases.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2407854-31-1 |
| Applications | DGKα/ζ Inhibitor |
| Formula | C26H22BrF2N5O3 |
| Molecular Weight | 570.39 |
| SMILES | CN(C1=CC=C(Br)N=C1C(N2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)=C5[N+]([O-])=O)C5=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.