Fig. 1 · Structure
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BMS-561392 formate
TACE Inhibitor
BMS-561392 formate is a potent inhibitor of TNF alpha-converting enzyme (TACE), also known as ADAM17. This compound selectively blocks TACE activity, resulting in the modulation of inflammatory processes. BMS-561392 formate is particularly useful for investigating the role of TACE in inflammatory bowel disease and other related inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2922280-85-9 |
| Applications | TACE Inhibitor |
| Formula | C28H34N4O6 |
| Molecular Weight | 522.59 |
| Synonyms | DPC 333 formate |
| SMILES | OC=O.N[C@]1(C2=CC=C(C=C2)OCC3=CC(C)=NC4=C3C=CC=C4)C(N(CC1)[C@H](CC(C)C)C(NO)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.