Fig. 1 · Structure
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BMS-587101
LFA-1 Antagonist
BMS-587101 is a potent, orally active antagonist of leukocyte function-associated antigen-1 (LFA-1). This compound exhibits significant anti-inflammatory effects, making it a valuable tool for research related to rheumatoid arthritis and other inflammatory conditions. Its mechanism of action can help elucidate the role of LFA-1 in immune response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 509083-77-6 |
| Applications | LFA-1 Antagonist |
| Formula | C26H20Cl2N4O4S |
| Molecular Weight | 555.43 |
| SMILES | O=C(C1=CSC(CN(C[C@H]2C3=CC=C(C#N)C=C3)C[C@]2(N(C)C(N4C5=CC(Cl)=CC(Cl)=C5)=O)C4=O)=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.