BMS-665053

Name: BMS-665053
Brand: Adooq Bioscience
SKU: A59745
Rating: 5 (288 reviews)

Catalog No.: A59745

CRFR Antagonist

BMS-665053 is a potent corticotropin-releasing factor-1 (CRF1) receptor antagonist, exhibiting an IC50 of 1.0 nM. This compound effectively inhibits CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells, with an IC50 of 4.9 nM. BMS-665053 is valuable for research in neuroendocrine regulation and stress response pathways.

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Grouped product items
Size	Price	Stock
25mg	$1,275.00	In stock
50mg	$1,625.00	In stock
100mg	$2,000.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	BMS-665053 is a potent corticotropin-releasing factor-1 (CRF1) receptor antagonist, exhibiting an IC50 of 1.0 nM. This compound effectively inhibits CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells, with an IC50 of 4.9 nM. BMS-665053 is valuable for research in neuroendocrine regulation and stress response pathways.

Product Information

Catalog Num	A59745
Formula	C16H14Cl3F2N3O2
Molecular Weight	424.66
CAS Number	1173435-64-7
SMILES	ClC1=CN([C@H](C2CC2)C)C(C(NC3=C(Cl)C=C(OC(F)F)C=C3Cl)=N1)=O

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