Fig. 1 · Structure
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BMS-763534
CRF1 Antagonist
BMS-763534 is a selective corticotropin-releasing factor 1 (CRF1) antagonist. It has demonstrated the ability to mitigate the effects of stress-related neurological disorders, including depression and anxiety. This compound is valuable in research aimed at understanding the role of the CRF1 receptor in mood regulation and the development of potential therapeutic strategies for stress-induced conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1188407-40-0 |
| Applications | CRF1 Antagonist |
| Formula | C18H21ClF2N4O3 |
| Molecular Weight | 414.83 |
| SMILES | O=C1C(NC2=CC(C)=C(N=C2C)OC(F)F)=NC(Cl)=CN1[C@H](COC)C3CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.