BMS-777607

Catalog No.: A10153

c-Met inhibitor

BMS-777607

BMS-777607 Chemical Structure

CAS NO. 1196681-44-3

BMS-777607 is a MET tyrosine kinase inhibitor that binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $350.00

Special Price $280.00

100 mg

Regular Price: $620.00

Special Price $496.00

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Biological Activity

BMS-777607 is a MET tyrosine kinase inhibitor that binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.5 mL 97.48 mL 194.97 mL
0.5 mM 3.9 mL 19.5 mL 38.99 mL
1 mM 1.95 mL 9.75 mL 19.5 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10153
Actions Inhibitor
CAS No. 1196681-44-3
Formula C25H19ClF2N4O4
M. Wt 512.9
Purity >98%
Synonyms BMS777607
SMILES CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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