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Biological Activity
BMS-777607 is a MET tyrosine kinase inhibitor that binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.5 mL | 97.48 mL | 194.97 mL |
| 0.5 mM | 3.9 mL | 19.5 mL | 38.99 mL |
| 1 mM | 1.95 mL | 9.75 mL | 19.5 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
*The above data is based on the productmolecular weight 512.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10153 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1196681-44-3 |
| Formula | C25H19ClF2N4O4 |
| M. Wt | 512.9 |
| Purity | >98% |
| Synonyms | BMS777607 |
| SMILES | CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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