BMS-8 is a selective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 7.2 μM. It directly binds to PD-L1, promoting the formation of PD-L1 homodimers, thereby obstructing the engagement with PD-1. This compound is primarily utilized in cancer immunotherapy research, particularly in studies focused on the modulation of immune checkpoint pathways.
BMS-8 is a selective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 7.2 μM. It directly binds to PD-L1, promoting the formation of PD-L1 homodimers, thereby obstructing the engagement with PD-1. This compound is primarily utilized in cancer immunotherapy research, particularly in studies focused on the modulation of immune checkpoint pathways.
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