Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

BMS-863233 (XL-413)

Catalog No.: A13677

CDK inhibitor

BMS-863233 (XL-413)

BMS-863233 (XL-413) Chemical Structure

CAS NO. 1169562-71-3

BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$95.00
10 mg
$162.00
25 mg
$285.00
50 mg
$475.00
10mM * 1mL in DMSO
$135.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Gijs Zonderland, .et al. The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition, Mol Cell, 2022, Sep 15;82(18):3350-3365 PMID: 36049481
  • Wang C, .et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer, Nature, 2019, Oct 2 PMID: 31578521

Biological Activity

BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity.
Targets
Cdc7 Pim1 CK2
3.4 nM42 nM212 nM
In vitro DMSO Insoluble
Water Warmed: 43 mg/mL (131.82 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.66 mL 153.29 mL 306.58 mL
0.5 mM 6.13 mL 30.66 mL 61.32 mL
1 mM 3.07 mL 15.33 mL 30.66 mL
5 mM 0.61 mL 3.07 mL 6.13 mL

*The above data is based on the productmolecular weight 326.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13677
Actions Inhibitor
CAS No. 1169562-71-3
Formula C14H13Cl2N3O2
M. Wt 326.18
Purity >98%
Synonyms BMS-863233; BMS863233; BMS 863233; XL-413; XL413; XL 413
SMILES C1C[[email protected]](NC1)C2=NC(=O)C3=C(N2)C4=C(O3)C=CC(=C4)Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy BMS-863233 (XL-413) | BMS-863233 (XL-413) Supplier | purchase | cost | manufacturer | order | distributor | buy 1169562-71-3| 1169562-71-3 Supplier | purchase 1169562-71-3 | 1169562-71-3 cost | 1169562-71-3 manufacturer | order 1169562-71-3 | 1169562-71-3 distributor
Rewards