Fig. 1 · Structure
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BMS-929075
HCV NS5B Replicase Inhibitor
BMS-929075 is a potent allosteric inhibitor targeting the HCV NS5B replicase with a palm site mechanism of action. This compound demonstrates high oral bioavailability, making it suitable for pharmacokinetic studies. Additionally, BMS-929075 exhibits cytotoxic effects, indicating potential applications in antiviral research and the development of therapeutic strategies against hepatitis C virus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1217338-97-0 |
| Applications | HCV NS5B Replicase Inhibitor |
| Formula | C31H24F2N4O3 |
| Molecular Weight | 538.54 |
| SMILES | O=C(C1=CC(C2=C(F)C3=C(OC(C4=CC=C(F)C=C4)=C3C(NC)=O)C=C2)=C(C)C=C1)NC5(CC5)C6=NC=CC=N6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.