Fig. 1 · Structure
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BMS-933043
α7 nACh Receptor Partial Agonist
BMS-933043 is a selective partial agonist of the α7 nicotinic acetylcholine receptor (nAChR). This compound has been shown to mitigate cognitive impairment in murine models, making it a valuable tool for research focused on cognitive dysfunction, particularly in the context of schizophrenia. Its unique mechanism facilitates the exploration of neuropsychological pathways and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 1221973-93-8 |
| Applications | α7 nACh Receptor Partial Agonist |
| Formula | C16H19N7O |
| Molecular Weight | 325.37 |
| SMILES | C1(CC2)[C@@]3(OC(NC4=NC=NC(N5C=CN=C5)=C4)=NC3)CN2CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.