BMS-986165

Catalog No.: A18726

TYK2 Inhibitor

BMS-986165

BMS-986165 Chemical Structure

CAS NO. 1609392-27-9

BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease.

Availability: In stock

Package Price Qty
2 mg
$250.00
5 mg
$520.00
10 mg
$800.00
50 mg
$2,500.00
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Biological Activity

BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.52 mL 235.04 mL
0.5 mM 4.7 mL 23.5 mL 47.01 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18726
Actions Inhibitor
M. Wt 425.46
Formula C20H19D3N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609392-27-9
Synonyms BMS-986165; BMS 986165; BMS986165;
SMILES O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]

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