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BMY 25282

MMC Analog

BMY 25282 is a mitomycin C (MMC) analog that primarily targets oxygen activation in hepatocytes. This compound effectively overcomes MMC tolerance in colon cancer cells and demonstrates inhibition of tumor growth in mouse models of leukemia and melanoma. BMY 25282 is a valuable reagent for research applications in cancers, including leukemia, melanoma, and colon cancer, contributing to the understanding of therapeutic resistance mechanisms and treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	88949-01-3
Applications	MMC Analog
Formula	C₁₈H₂₃N₅O₅
Molecular Weight	389.41
Synonyms	BL 6782
SMILES	CO[C@]12N(C[C@H]3[C@@H]2N3)C4=C(C(C(/N=C/N(C)C)=C(C)C4=O)=O)[C@H]1COC(N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.