Fig. 1 · Structure

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BO 1341

PBPs Inhibitor

BO 1341 is a potent inhibitor of penicillin-binding proteins (PBPs), designed as an antipseudomonal semisynthetic cephalosporin. It demonstrates significant antibacterial activity against various Gram-negative pathogens, including Pseudomonas aeruginosa (MIC90: 1.56 μg/mL), Pseudomonas maltophilia (MIC50: 1.56 μg/mL), and Acinetobacter calcoaceticus (MIC90: 3.13 μg/mL). BO 1341 serves as a valuable tool in the investigation of infectious diseases and antibiotic resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 119068-46-1
Applications PBPs Inhibitor
Formula C26H24N6O9S2
Molecular Weight 628.63
SMILES
[O-]C(C1=C(C[N+]2=CC3=CC(O)=C(O)C=C3C=C2)CS[C@@]([C@@H]4NC(/C(C5=CSC(N)=N5)=N/OC(C)(C)C(O)=O)=O)([H])N1C4=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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