Fig. 1 · Structure
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Boc-L-2,4-Diaminobutyric acid
ASCT2 Ligand
Boc-L-2,4-Diaminobutyric acid is a potent ligand for the amino acid transporter ASCT2 (SLC1A5). This compound serves as a valuable synthetic building block for the development of ASCT2 inhibitors and bioactive molecules. Its cleavable protecting group reduces backbone cleavage rates while facilitating intramolecular cyclization of self-immolative linkers under acidic conditions. Additionally, Boc-L-2,4-Diaminobutyric acid can be utilized as an internal standard for the quantitative detection of specific intracellular amino acids via UPLC-QQQ-MS, making it a versatile reagent in chemical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 25691-37-6 |
| Applications | ASCT2 Ligand |
| Formula | C9H18N2O4 |
| Molecular Weight | 218.25 |
| Synonyms | N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.