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Boc-MIF-1-Am

hD2R Activator

Boc-MIF-1-Am is a potent enhancer of the human dopamine D2 receptor, exhibiting an EC50 value of 17.82 nM. This bioconjugate of melanostatin (MIF-1) and amantadine is primarily utilized in the study of dopaminergic signaling pathways and their implications in neurological disorders. Although Boc-MIF-1-Am demonstrates key biological activity, it has been noted to exhibit mild neurotoxicity at a concentration of 200 μM in SH-SY5Y cells, making careful consideration necessary in experimental designs.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3056144-84-1
Applications	hD2R Activator
Formula	C₂₈H₄₆N₄O₅
Molecular Weight	518.69
SMILES	O=C(N[C@@H](CC(C)C)C(NCC(NC1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)=O)=O)[C@H]4N(C(OC(C)(C)C)=O)CCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.