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Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP

β-glucuronide-type Linker Precursor

Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP is a β-glucuronide-type linker precursor designed for synthesizing the NeoDegrader P1-β-Glucuronide Linker Complex when coupled with NeoDegrader P1. This compound facilitates the formation of linker-payload complexes, which are valuable for investigating therapeutic approaches in acute myeloid leukemia. Its unique chemical structure supports research aimed at targeted drug delivery and the development of novel treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2874333-81-8
Applications	β-glucuronide-type Linker Precursor
Formula	C₃₅H₄₁N₃O₁₈
Molecular Weight	791.71
SMILES	CC(O[C@H]([C@H]([C@@H]([C@H](O1)C(OC)=O)OC(C)=O)OC(C)=O)[C@@H]1OC2=C(C=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)C(NCCNC(OC(C)(C)C)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.