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Boc-PNA-thioU(PMB)-OH

PNA Monomer

Boc-PNA-thioU(PMB)-OH is a peptide nucleic acid (PNA) monomer featuring a PMB protecting group on thiouracil, which increases its binding affinity to adenine. This compound demonstrates significant resistance to enzymatic degradation and enhanced hybridization capabilities. It is particularly suitable for applications in gene diagnostics, antisense therapy, and various molecular biology research areas that necessitate robust binding strength and functional versatility.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	253438-99-2
Applications	PNA Monomer
Formula	C₂₃H₃₀N₄O₇S
Molecular Weight	506.57

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.