Fig. 1 · Structure
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Bofumustine
Nitrosylurea Anticancer Compound
Bofumustine is a nitrosourea compound recognized for its antitumor activity. It exerts its effects by alkylating DNA, thereby disrupting replication and division processes in cancer cells, which ultimately leads to cell death. Bofumustine is applicable in cancer research, providing insights into mechanisms of tumor biology and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 55102-44-8 |
| Applications | Nitrosylurea Anticancer Compound |
| Formula | C18H21ClN4O9 |
| Molecular Weight | 472.83 |
| Synonyms | ICIG 1105; NSC 279194; RFCNU |
| SMILES | ClCCN(N=O)C(NC1[C@@]2([H])[C@@](OC(C)(C)O2)([H])[C@@H](COC(C3=CC=C([N+]([O-])=O)C=C3)=O)O1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.