Fig. 1 · Structure
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BoNT-IN-2
BoNT/A LC Inhibitor
BoNT-IN-2 is a Botulinum Neurotoxin A Light Chain (BoNT/A LC) inhibitor, exhibiting an IC50 of 4.5 μM. This compound effectively interferes with the enzymatic activity of BoNT/A, making it a valuable tool for studying the mechanisms of neurotoxin action and its biological effects. Research applications include exploring synaptic transmission and potential therapeutic interventions in toxin-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 354784-03-5 |
| Applications | BoNT/A LC Inhibitor |
| Formula | C25H26N4O |
| Molecular Weight | 398.50 |
| SMILES | OC1=C2N=C(C)C=CC2=CC=C1C(C3=CC=C(N(C)C)C=C3)NC4=NC(C)=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.