Fig. 1 · Structure
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Bopindolol fumarate
β-Adrenoceptors Antagonist
Bopindolol fumarate is a non-selective antagonist of β-adrenoceptors, exhibiting partial agonist activity primarily at β1- and β2-ARs, with minimal affinity for the β3 subtype. This compound possesses intrinsic sympathomimetic properties, membrane stabilizing effects, and the ability to inhibit renin secretion, while also interacting with 5-HT receptors. Bopindolol fumarate is a useful reagent for studies involving essential and renovascular hypertension, contributing valuable insights into cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 79125-22-7 |
| Applications | β-Adrenoceptors Antagonist |
| Formula | C27H32N2O7 |
| Molecular Weight | 496.55 |
| Synonyms | (±)-Bopindolol fumarate |
| SMILES | CC(N1)=CC2=C1C=CC=C2OCC(OC(C3=CC=CC=C3)=O)CNC(C)(C)C.O=C(O)/C=C/C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.