Fig. 1 · Structure
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Bopindolol
β-Adrenoceptors Antagonist
Bopindolol is a β-adrenoceptor antagonist with partial agonist activity, exhibiting non-selective binding to β1- and β2-ARs, while displaying low affinity for the β3-AR subtype. This compound possesses intrinsic sympathomimetic properties and membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol is utilized in research focused on essential and renovascular hypertension, serving as a proagent for Pindolol.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 62658-63-3 |
| Applications | β-Adrenoceptors Antagonist |
| Formula | C23H28N2O3 |
| Molecular Weight | 380.48 |
| Synonyms | (±)-Bopindolol |
| SMILES | CC(N1)=CC2=C1C=CC=C2OCC(OC(C3=CC=CC=C3)=O)CNC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.