Fig. 1 · Structure
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BPAM344
Kainate Receptor PAMs
BPAM344 is a positive allosteric modulator (PAM) of kainate receptors (KAR), specifically targeting the GluK1b, GluK2a, and GluK3a subunits. This compound enhances receptor activation and signaling, playing an important role in neuropharmacology research. BPAM344 is valuable for studying synaptic transmission and neurodegenerative diseases, providing insights into the modulation of excitatory neurotransmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1204572-55-3 |
| Applications | Kainate Receptor PAMs |
| Formula | C10H11FN2O2S |
| Molecular Weight | 242.27 |
| SMILES | FC1=CC=C(C2=C1)N(C3CC3)CNS2(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.