Fig. 1 · Structure
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BPDBA
BGT-1 Inhibitor
BPDBA is a selective, noncompetitive inhibitor of the betaine/GABA transporter (BGT-1), exhibiting IC50 values of 20 μM and 35 μM for human BGT-1 and mouse GAT2, respectively. This compound effectively modulates neurotransmitter transport, making it a valuable tool for research into neurological disorders and transporter-related studies. Its distinct inhibitory profile can facilitate investigations into the roles of BGT-1 in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 312281-74-6 |
| Applications | BGT-1 Inhibitor |
| Formula | C19H20Cl2N2O |
| Molecular Weight | 363.28 |
| SMILES | O=C(NC1CCN(CC2=CC=CC=C2)CC1)C3=CC=C(Cl)C=C3Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.