Fig. 1 · Structure

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BPH-652

CrtM Inhibitor

BPH-652 is a potent inhibitor of the S. aureus dehydrosqualene synthase (CrtM), demonstrating a Ki of 1.5 nM and an IC50 range of 100-300 nM in the modulation of S. aureus pigment formation. This compound serves as a valuable tool for investigating the biosynthesis of isoprenoids and developing novel antimicrobial strategies targeting bacterial infections. Its specificity and efficiency make it suitable for research applications focused on understanding the roles of CrtM in pathogenesis and resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 157124-84-0
Applications CrtM Inhibitor
Formula C16H16K3O7PS
Molecular Weight 500.63
SMILES
O=S(C(P(O[K])(O[K])=O)CCCC1=CC=CC(OC2=CC=CC=C2)=C1)(O[K])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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