BPN14770

Catalog No.: A18663

PDE4D inhibitor

BPN14770

BPN14770 Chemical Structure

CAS NO. 1606974-33-7

BPN14770 is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor with IC50s of 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3, respectively.

Availability: In stock

Package Price Qty
5 mg
$250.00
10 mg
$450.00
50 mg
$1,500.00
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Biological Activity

BPN14770 is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor with IC50s of 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3, respectively.
In vitro DMSO 71 mg/mL (174.96 mM)
Water <1 mg/mL
Ethanol 71 mg/mL (174.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.64 mL 123.21 mL 246.43 mL
0.5 mM 4.93 mL 24.64 mL 49.29 mL
1 mM 2.46 mL 12.32 mL 24.64 mL
5 mM 0.49 mL 2.46 mL 4.93 mL

*The above data is based on the productmolecular weight 405.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18663
Actions Inhibitor
CAS No. 1606974-33-7
Formula C21H15ClF3NO2
M. Wt 405.8
Purity >98%
Synonyms BPN 14770, BPN-14770
SMILES O=C(O)CC1=CC=C(CC2=CC(C3=CC=CC(Cl)=C3)=NC(C(F)(F)F)=C2)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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