Fig. 1 · Structure
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BPR1R024
c-Fms Inhibitor
BPR1R024 is a selective inhibitor of the colony-stimulating factor-1 receptor (CSF1R) with oral bioavailability. It exhibits potent inhibition of CSF1R, demonstrating an IC50 value of 0.53 nM. This compound is valuable for research applications in immuno-oncology, investigating the role of CSF1R in tumor microenvironments and immune modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2503015-75-4 |
| Applications | c-Fms Inhibitor |
| Formula | C24H21F3N6O2 |
| Molecular Weight | 482.46 |
| SMILES | CN(C1=CC2=C(C(OC3=CC=C(C=C3)NC(NCC4=CC=C(N=C4)C(F)(F)F)=O)=NC=N2)C=C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.