Fig. 1 · Structure

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bpV(bipy) hydrate

PTEN Inhibitor

bpV(bipy) hydrate is a potent inhibitor of phosphoinositide 3-phosphatase (PTEN) as well as protein tyrosine phosphatases PTP-β and PTP-1B, exhibiting IC50 values of 18 nM, 60.3 nM, and 164 nM, respectively. Its primary mechanism facilitates the modulation of signaling pathways involved in cell growth, survival, and metabolism. bpV(bipy) hydrate is valuable for research applications focused on cancer biology, neurobiology, and the exploration of therapeutic strategies targeting PTEN-related signaling.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1173697-60-3
Applications PTEN Inhibitor
Formula C10H16KN2O9V
Molecular Weight 398.28
SMILES
O=[V+3]123([O-][O-]2)([N]4=C(C5=[N]3C=CC=C5)C=CC=C4)[O-][O-]1.[K+].O.O.O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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