Fig. 1 · Structure
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BpV(pic) potassium hydrate
PTEN Inhibitor
BpV(pic) potassium hydrate is a potent inhibitor of the phosphatase and tensin homolog (PTEN) with an IC50 of 31 nM. This compound also acts as an insulin mimetic, promoting insulin receptor kinase activation in liver cancer cells and enhancing adipogenesis in adipocytes. Additionally, BpV(pic) potassium hydrate effectively inhibits the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors, making it a valuable tool for studies in cancer biology and metabolic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 148556-27-8 |
| Applications | PTEN Inhibitor |
| Formula | C6H8K2NO9V32- |
| Molecular Weight | 469.15 |
| SMILES | O=[V]123([O-][O-]2)([O-][O-]3)([V][V+])[N](C=CC=C4)=C4C([O-]1)=O.[K+].O.O.[K+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.